<?xml version="1.0" encoding="UTF-8"?>
<?xml-stylesheet type="text/xsl" href="../../xsl/transcript_eng.xsl"?>
<tt xmlns:tts="http://www.w3.org/2006/04/ttaf1#styling" xml:lang="en">
  <head>
    <styling>
      <style id="defaultSpeaker" tts:fontSize="12px" tts:fontFamily="SansSerif" tts:fontWeight="normal" tts:fontStyle="normal" tts:textDecoration="none" tts:color="white" tts:backgroundColor="black" tts:textAlign="left" />
      <style id="defaultCaption" tts:textAlign="center" />
    </styling>
  </head>
  <body id="thebody" style="defaultCaption">
    <div xml:lang="en">
      <video_title>How can Neanderthal DNA tell us about ourselves?</video_title>
	  <video_subject_name>Ed Green | Research Scientist, Evolutionary Genetics</video_subject_name>
	  <video_subject_title>Max Planck Institute for Evolutionary Anthropology</video_subject_title>
      <p begin="0:00:00.93" end="0:00:08.71">The main question that we are investigating with this project is how Neanderthals look,</p>
      <p begin="0:00:08.74" end="0:00:15.58">genetically, compared to humans and other primates.</p>
      <p begin="0:00:15.62" end="0:00:20.09">What makes it possible, and what really makes it interesting, is the technological advances</p>
      <p begin="0:00:20.12" end="0:00:25.83">that have happened that allow us to recover this DNA that's 38,000 years old</p>
      <p begin="0:00:25.86" end="0:00:28.16">and get some sequence from this.</p>
      <p begin="0:00:28.20" end="0:00:34.03">Are there any genes that come from Neanderthal in humans today?</p>
      <p begin="0:00:34.07" end="0:00:38.27">Are there any genes from modern humans in Neanderthal?</p>
      <p begin="0:00:38.31" end="0:00:41.38">Was there any admixture between the two?</p>
      <p begin="0:00:41.41" end="0:00:45.55">And one final question that we would like to ask is:</p>
      <p begin="0:00:45.58" end="0:00:50.85">When did the evolutionary changes that are specific to modern humans--</p>
      <p begin="0:00:50.88" end="0:00:57.62">that are unique to us compared to all other of the animals of the world--when did these evolve?</p>
      <p begin="0:00:57.66" end="0:01:03.00">And using the Neanderthal, we can get some resolution on this</p>
      <p begin="0:01:03.03" end="0:01:07.40">that is impossible to get from any organism that's living today.</p>
      <p begin="0:01:07.43" end="0:01:12.94">So, in some sense, the most important contribution of the Neanderthal genome</p>
      <p begin="0:01:12.97" end="0:01:16.61">will not be telling us something about Neanderthals,</p>
      <p begin="0:01:16.64" end="0:01:19.88">but rather will be telling us something about modern humans.</p>
    </div>
  </body>
</tt>

