Red blood cells from an individual with sickle cell disease are induced to change shape from normal, round donut shape, to sickle like, starburst shape. Visitors view the process under a video microscope. Pressing a button bathes the round red blood cells in a solution low in oxygen, causing the hemoglobin in the blood cells to give up their oxygen. When sickling hemoglobin loses oxygen, it clumps together, forcing the cells to sickle. Pressing another button introduces an oxygen rich solution, and the sickled cells regain their normal shape.